Paul Rabinow's work has consistently centered on modernity as a problem: problem for those seeking to live with its diverse forms, a problem for those seeking to advance or resist modern projects of power and knowledge. This work has ranged from descendants of a Moroccan saint coping with the changes wrought by colonial and post-colonial regimes, to the wide array of knowledges and power relations entailed in the great assemblage of social planning in France, to my work of the last decade on molecular biology and genomics. His current research centers on developments in post-genomics and molecular diagnostics. It seeks to invent an analytic framework to understand the issues of bio-politics and bio-security. A related research interest is the contemporary moral terrain with special attention to "affect."